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DNA tests reveal similarities to early wet-rice farmers Some of the first wet-rice farmers in Japan might have migrated from the lower basin of China's Yangtze River more than 2,000 years ago, Japanese and Chinese researchers said Thursday. This was suggested by DNA tests conducted by the researchers that showed genetic similarities between human remains from the Yayoi Period found in southwestern Japan and the early Han Dynasty found in China's central Jiangsu Province, Satoshi Yamaguchi told reporters. People who introduced irrigation techniques to the Japanese archipelago in the Yayoi Period (250 B.C.-300) were believed to have come to Japan either from the Korean Peninsula across the Tsushima Strait, or from northern China across the Yellow Sea. The latest findings, however, bolster another theory suggesting the origin of the Yayoi people was an area south of the Yangtze, which is believed to be the birthplace of irrigated rice cultivation. Yamaguch...

Dual origin hypothesis Previous studies showed genetic affinities between the Ainu and Ryukyu peoples,who live in the north and south ends of Japan, respectively, and who are thought to be descendents of the Jomon people. These observations are consistent with the “dual-origin hypothesis”, which states that the ancestral Japanese populations were brought by two major migration events. Archeological studies have suggested that the Jomon period (the Japanese Neolithic age) started about (14000 - 300 BC), when the Yayoi period(300 BC - 250 AD), a rice-farming and metal-using age, started. In the Yayoi period, immigrants from the Asian continent had moved to western Japan via Korea or China and expelled or mixed with the Jomon people. Our observations of the two main clusters and genetic differentiation among geographic regions are not discordant with the dual-origin hypothesis, although most of the Hokkaido individuals in this study are probably different from the indigenous Ainu people...

The majority of chinese are from haplogroup O3. And the migration is from north china, during Han漢-Tang唐 dynasty ( 1700 years ago) and Han漢-Song宋 dynasty ( 800 years ago)   from genebase Among all the populations of East and Southeast Asia, Haplogroup O3 is most closely associated with those that speak a Sinitic, Tibeto-Burman, or Hmong-Mien language. Haplogroup O3 comprises about 50% or more of the total Y-chromosome variation among the populations of each of these language families. The Sinitic and Tibeto-Burman language families are generally believed to be derived from a common Sino-Tibetan protolanguage, and most linguists place the homeland of the Sino-Tibetan language family somewhere in northern China. The Hmong-Mien languages and cultures, for various archaeological and ethnohistorical reasons, are also generally believed to have derived from a source somewhere north of their current distribution, perhaps in northern or central China. The Tibetans, however, des...

hunger and appetite hormone Hormonal Imbalance, Sleep And Menopause Causes Obesity Through neurobiological data, presence of food cravings, over eating, and tolerance support an addiction-like model by numerous signals that are involved in engaging both the central and peripheral nervous system in a bi-directional manner to regulate food intake. Genes, environment, various emotions also influence food intake, and mood states that trigger eating of palatable foods for comfort in negative emotional states. This repetitive eating of comfort foods, rich in carbohydrate, high-fats and sugar, leads to obesity. Obesity in turn regulates mood due to metabolic disturbances. Metabolic disturbances further alter brain-signaling systems leading to a bi-directional vicious cycle of mood, food, and obesity . Furthermore a complex regulation of mood and eating disorders are implied from emerging studies of epigenetics in mood and eating disorders. frontiers the sci...

Dr Fuhrman's website

What is the optimal level of gene expression throughout life? The answer will differ from one individual to another. One way to answer the question is to establish a baseline biomarker profile based on measurements taken in late adolescence or early adulthood. This allows the anti-aging practitioner to do more than make an educated guess based on the mythical average for a specific biomarker. The ideal would be to perform a complete biomarker survey at or before age thirty to determine an individual's baseline biomarker levels. But even if your thirtieth birthday has long since passed, it isn't too late to find your own current baseline. Without it, you will never know for sure how close you have come to achieving your genetic goals. The technology of gene banking makes it possible to store and document our genetic profile regardless of our age. As with baseline biomarker assessment, the ideal time to do this is during late adolescence or early adulthood. People who wish to p...

Hormonal replacement with the triestrogens ( estradiol, estriol and estrone) is recommended for women to mimic the body's natural levels of these hormones. The suggested dose is 1.25 to 5 grams applied to the skin twice daily until symptoms of deficiency ( such as hot flashes and vaginal dryness) are eliminated. The ideal approach is to use the lowest dose possible to eliminate symptoms. Progesterone replacement should start with 20 to 200 mg twice a day in the form of a transdermal cream. Progesterone can also be given orally in a dosage of 50 to 250 mg daily ( the usual dose is 100 mg) before bedtime. If hormone creams are used, they are applied twice daily, morning and evening, to maintain stable blood levels around the clock. Symptoms of progesterone deficiency - water retention, width gain, bone loss, anxiety, sleep problem, painful breasts, and shorter menstrual cycles - should also be monitored until subjective improvement is documented.